Solitary Expression of CD7 Among T-cell Antigens in Acute Myeloid Leukemia: Rearrangements and Course of Disease Suggestive of Poor Prognosis Identification of a Group of Patients With Similar T-cell Receptor

In a series of 100 acute myeloid leukemia (AML) patients defined by cytochemistry and immunophenotyping, 20 expressed T-lymphocyte associated antigens on the surface of their blasts. While 15 expressed two or more T-cell antigens, five were found to express only CD7. All patients belonged to the French-American-British type M4, and four were under the age of 40. Despite intensive chemotherapy, four never obtained a complete remission and the f i ih died of relapse after an allogenic bone marrow transplantation. While 12 randomly selected T-cell antigen negative AML patients